STAT3 抗体: Biotin
英文名称： STAT3 Antibody: Biotin
型号:null    抗体货号： SPC-1334D-BI
价格:请致电：010-57128832,18610462672
品牌: 加拿大    产品商标: stressmarq

信号传导子及转录激活子3抗体-兔抗人STAT3 多克隆抗体, 适用物种: 人 | 小鼠 | 大鼠. 适用应用: WB | IHC

薷矗�
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量26kDa
细胞定位细胞核 细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human KCTD5
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
KCTD5,钾离子通道四聚体结构域蛋白5抗体PubMedPubMed
产品介绍background:
The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KCTD5 (potassium channel tetramerisation domain containing 5) is a 234 amino acid protein that localizes predominantly in the cytoplasm but translocates to the nucleus upon interaction with REP proteins. Existing as a homopentamer and consisting of one BTB (POZ) domain, KCTD5 associates with GRASP55, CUL-3 and ubiquitinated proteins. Interaction with CUL-3 suggests KCTD5 functions as a substrate adapter protein in some E3 ligase complexes.

Subunit:
Homopentamer. Interacts (via C-terminus) with GRASP55/GORASP2. Interacts with CUL3 and with ubiquitinated proteins. Interacts with adeno-associated virus 2 (AAV-2) REP proteins.

Subcellular Location:
Cytoplasm, cytosol. Nucleus. Note=Predominantly cytoplasmic, translocated to the nucleus upon interaction with Rep proteins.

Similarity:
Contains 1 BTB (POZ) domain.

Gene ID:
54442

KCTD5,钾离子通道四聚体结构域蛋白5抗体Database links:
Entrez Gene: 54442 Human
Omim: 611285 Human
SwissProt: Q9NXV2 Human
Unigene: 61960 Human


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.