Anti-SHANK1/SHANK3 mAb: ATTO 390 [S367-51]
英文名称: SHANK1/SHANK3 Monoclonal Antibody: ATTO 390 [S367-51]
型号:null    抗体货号: SMC-460D-A390
价格:请致电:010-57128832,18610462672
品牌: 加拿大    产品商标: stressmarq

SHANK proteins are scaffolding adaptors that have been shown to integrate neurotransmitter receptors into the cortical cytoskeleton at postsynaptic densities. SHANK1-3 of the SHANK/ProSAP family are molecular scaffolds in the postsynaptic density (PSD). SHANK recruits betaPIX and PAK to dendritic spines to regulate postsynaptic structure and interacts with ionotropic receptor and metabotropic glutamate receptor complexes. Transcript splice variation in the Shank family influences the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain to ensure normal development.