The Kv4.2 potassium channel is a voltage-gated channel protein which belongs to the delayed rectifier class and to the ShaI potassium channel subfamily (3). All of the KV channels can product delayed-rectifier and transient “A-type” currents, all members of the KV4 subfamily mediate IA (3). Kv4 channels in the central nervous system localize to the soma and dendrites, and therefore are responsible for the somato-dendritic A-type K+ current (ISA) (3,4).