The p53 protein (tumor protein 53 or TP53) is a DNA-binding cell cycle-regulating transcriptionfactor that governs cell division and the finebalance between cell death and cell survival (1).P53 plays a critical role in tumor suppression andhence it is often described as "the guardian of thegenome", "the guardian angel gene", or the "masterwatchman." This also refers to its role in conservingstability by preventing genome mutation (2).Defects in p53 are linked to >50% of humancancers, and restoring p53 function to thesecancer cells can induce growth arrest andapoptosis (3). When p53 has been damaged, itcan also lead to autoimmune disorders (4, 5).