Kv1.1, also known as potassium voltage-gated channel subfamily A member 1, is a shaker related voltage potassiumchannel that in humans is encoded by the SCNA1 gene (3-5).It is strongly expressed in a variety of neurons in adultrodents, and it appears to be involved in regulating neuronalexcitability. Specifically it plays a role in severaldevelopmental processes including proliferation, migrationand cell-cell adhesion (6). The Isaacs syndrome is a result ofan autoimmune reaction against the Kv1.1 ion channel (7).