LAS2,肺腺瘤易感蛋白2抗体
英文名称: Anti-LAS2 antibody
型号:null    抗体货号: HZ-9672R
价格:请致电:010-57128832,18610462672
品牌: 中国/美国    产品商标: hzbscience

LAS2,肺腺瘤易感蛋白2抗体

产品编号HZ-9672R
英文名称LAS2
中文名称肺腺瘤易感蛋白2抗体
别 名Chromosome 18 open reading frame 54; Hypothetical protein LOC162681; LAS2; Lung adenoma susceptibility protein 2; MGC33382; Uncharacterized protein C18orf54; LAS2_HUMAN.
说 明 书0.1ml 0.2ml
研究领域心血管 细胞生物 免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Pig,
LAS2,肺腺瘤易感蛋白2抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量39/60kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human LAS2/C18orf54
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
LAS2,肺腺瘤易感蛋白2抗体PubMedPubMed
产品介绍background:
Encoding over 300 genes, chromosome 18 contains about 76 million bases. Trisomy 18, or Edwards syndrome, is the second most common trisomy after Downs syndrome. Symptoms of Edwards syndrome include low birth weight, a variety of physical development defects, heart deformations and breathing difficulty. Translocation between chromosome 18 and 14 is the most common translocation in cancers, and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18. The TGFβ modulators, Smad2, Smad4 and Smad7 are encoded by chromosome 18. The C18orf54 gene product has been provisionally designated C18orf54 pending further characterization.

Function:
Might play a role in cell proliferation.

Subcellular Location:
Secreted.

Database links:
Entrez Gene: 162681 Human
Omim: 613258 Human
SwissProt: Q8IYD9 Human
Unigene: 208701 Human

LAS2,肺腺瘤易感蛋白2抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

evel). Expressed in testicular cancer (at protein level). Expressed weakly in heart, placenta, skeletal muscle, bone marrow, colon, kidney, salivary glands, testis and pancreas. Detected in fetal liver, fetal ovary, gonocytes and interstitial cells of the testis.

Similarity:
Belongs to the RRM IMP/VICKZ family br>Contains 4 KH domains.
Contains 2 RRM (RNA recognition motif) domains.

Gene ID:
10644

IGF2BP2,胰岛素样生长因子ⅡmRNA结合蛋白2抗体Database links:
Entrez Gene: 10644 Human
Entrez Gene: 319765 Mouse
Entrez Gene: 303824 Rat
Omim: 608289 Human
SwissProt: Q9Y6M1 Human
SwissProt: Q5SF07 Mouse
Unigene: 35354 Human
Unigene: 489442 Mouse
Unigene: 17318 Rat


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.