CRLS1,心磷脂合成酶1抗体
英文名称: Anti-CRLS1 antibody
型号:null    抗体货号: HZ-14063R
价格:请致电:010-57128832,18610462672
品牌: 中国/美国    产品商标: hzbscience

CRLS1,心***脂合成酶1抗体

产品编号HZ-14063R
英文名称CRLS1
中文名称心***脂合成酶1抗体
别 名0610009I22Rik; 4930557M15Rik; 5730490M08; C20orf155; Cardiolipin synthase 1; Cardiolipin synthase; CLS; CLS1; CRLS1; CRLS1_HUMAN; dJ967N21.6; GCD10; OTTMUSP00000016677; Protein GCD10 homolog; RGD1311037; RP23-77H16.4.
说 明 书0.1ml 0.2ml
研究领域肿瘤 心血管 细胞生物 信号转导 新陈代谢
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
CRLS1,心***脂合成酶1抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量33kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human CRLS1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CRLS1,心***脂合成酶1抗体PubMedPubMed
产品介绍background:
Cardiolipin synthetase is a mitochondrial protein that belongs to the CDP-alcohol phosphatidyltransferase class-I family. CLS1 is a multi-pass membrane protein localized to the inner membrane of mitochondria. CLS1 is responsible for the catalyzing the reversible transfer of a phosphatidyl group from one phosphatidyl glycerol molecule to another. This process results in the formation of cardiolipin (CL, or diphosphatidyl glycerol) and glycerol. Diphosphatidyl glycerol is a major component of the mitochondrial membrane and constitutes roughly 20% of total mitochondrial lipids. Having four fatty acid tails rather than the usual two, CL is a double phospholipid that is synthesized in the mitochondrion itself. Defects in the CRLS1 gene are likely to effect metabolism, sustained production of ATP and could contribute to diseases such as Barth syndrome.

Function:
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.

Subcellular Location:
Mitochondrion inner membrane.

Tissue Specificity:
Highly expressed in tissues such as heart, skeletal muscle and liver.

Post-translational modifications:


Similarity:
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

Gene ID:
54675

CRLS1,心***脂合成酶1抗体Database links:
Entrez Gene: 54675 Human
Omim: 608188 Human
SwissProt: Q9UJA2 Human
Unigene: 224764 Human


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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