【产品形式】：艾美捷为您提供的【PRMT1】重组人蛋白质精氨酸甲基转移酶-1蛋白产品是过滤灭菌的无色溶液；其中人蛋白质精氨酸甲基转移酶-1（PRMT1）产品溶解于40mM Tris-HCl pH 8.0, 100mM NaCl, 4mM MgCl2, 2mM DTT，40%甘油溶液中。人蛋白质精氨酸甲基转移酶-1（PRMT1）溶液可以在4℃冷藏保存4周；如果想延长保存时间，建议分装（加载体蛋白如0.1% HSA或 BSA）后置于-18℃冻存。请避免反复冻融。
【背景资料】：PRMT1 Methylates (mono & asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in a glycine and arginine-rich domain (may methylate HNRNPA1 and histones). Methylates SUPT5H.The PRMT1 protein functions as a histone methyltransferase specific for H4.PRMT1 is an essential factor in oncogenesis and is a potential novel therapeutic target in cancer.PRMT1-mediated methylation serves as a positive modulator of IR/IRS-1/PI3K pathway and glucose uptake in skeletal muscle cells.CAF1 is a new regulator of PRMT1-dependent arginine methylation.PRMT1 arginine-methylates MRE11 therefore it regulates the activity of MRE11-RAD50-NBS1 complex during the intra-S-phase DNA damage checkpoint response.PRMT1 plays a post-translationally part in regulating the transcriptional activity.PRMT1 is found predominantly in the cytoplasma though a fraction of PRMT1 is located in the nucleus. 
以色列ProSpec-Tany公司专注于细菌来源重组蛋白质生产。其独有细菌和哺乳动物表达和蛋白折叠技术使其成为国际一流科研级蛋白供应商。ProSpec-Tany是世界上能提供蛋白种类最多公司之一。领先生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。作为多家知名品牌代理，艾美捷与ProSpec一起为研究者们提供最好、最新细胞生物学研究工具而不断扩大产品及服务质量。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看中国生命科学试剂产品评论网站。
点击【PRMT1】重组人蛋白质精氨酸甲基转移酶-1查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-868垂询Prospec中国区域授权总代理艾美捷科技有限公司。