【Pleiotrophin】重组人多效生长因子 | Recombinant Human Pleiotrophin
英文名称: Recombinant Human Pleiotrophin
型号:null    产品货号: CYT-451
价格:请致电:010-57128832,18610462672
品牌: 美国

【产品形式】:艾美捷为您提供的【Pleiotrophin】重组人多效生长因子蛋白产品是是在大肠杆菌中重组表达的,分子量为17.3kDa,包含有人多效生长因子的136个氨基酸残基和16个额外的氨基酸残基His标签。该人多效生长因子重组蛋白最终由标准的色谱技术纯化出。

【背景资料】:Pleiotrophin (Osteoblast-Specific Factor-1,OSF-1) contains 136 amino acid residues. The sequence is very rich in cationic amino acids (24% of the residues); lysine cluster sequences are found in the N-terminal and C-terminal ends of the structure.The OSF-1 gene was shown by Northern blotting analysis to be expressed in mouse calvarial osteoblast-enriched cells and in mouse brain tissues,but not in thymus,spleen,kidney,liver,lung,testis or heart. Pleiotrophin has the ability to promote adhesion,migration,expansion,and differentiation of human osteoprogenitor cells. In addition to certain types of cancer,the embryonic growth and differentiation factor pleiotrophin is found also in adults in inflammatory diseases. In osteoarthritis,pleiotrophin is especially expressed in early stages,and its concentrations in the synovial fluid could serve as a marker for the progress of the disease. Pleitrophin might be involved in cartilage repair in osteoarthritis,in particular,in earlier stages.

Prospec

以色列ProSpec-Tany公司专注于细菌来源重组蛋白质生产。其独有细菌和哺乳动物表达和蛋白折叠技术使其成为国际一流科研级蛋白供应商。ProSpec-Tany是世界上能提供蛋白种类最多公司之一。领先生产工艺和规模使其可以提供毫克到克级蛋白,价格优于同类公司。作为多家知名品牌代理,艾美捷与ProSpec一起为研究者们提供最好、最新细胞生物学研究工具而不断扩大产品及服务质量。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看中国生命科学试剂产品评论网站。

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