Human Growth Factors & Cytokines
Recombinant Human IL-31


 
		Synonyms :
none.
		Description :
Human IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1.  It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant IL-31 is a 15.8 kDa protein containing 141 amino acid residues.
		Catalog #:
200-31
		Source :
E.coli
		Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses
		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
		Biological Activity :
Measured by its ability to induce STAT3 activation in human U87 cells.
                AA Sequence :
SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T 
		PubMed Link :
IL-31
Country of Origin :
USA
        Size A
2μg
$80 
 
 
        Size B
10μg
$195 
 
 
        Size C
1mg
$5200 
 
 
Special                     Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.
Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.