Recombinant Human FGF-10
 
Catalog Number:
AF-100-26
Synonyms:
Fibroblast Growth Factor-10, FGFA, Keratinocyte growth factor-2
Description:
FGF-10 is a heparin binding growth factor that belongs to the FGF family.  Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation.  FGF-10 is most related to KGF/FGF-7 and is expressed during the development and preferentially in adult lungs.  It signals through the FGFR 2b.  Recombinant human FGF-10 is a 19.3 kDa protein consisting of 170 amino acid residues. Manufactured using all non-animal reagents.
AA Sequence:
MLGQDMVSPE ATNSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS
Source:
E.coli
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors.  The expected ED50 is ≤ 0.5 ng/ml corresponding to a specific activity of ≥ 2 x 106 units/mg.
 
 
 
 
Research Interests:
Angiogenesis/ Cardiovascular
FGF Superfamily
Proliferation
Stem Cells & Differentiation
Wound Healing
 
 
 
Country of Origin:
USA
Research Use Only. Not for use in diagnostic or therapeutic procedures.