Synonyms : | none. |
Description : | Activin A is a TGF-β family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in post-menopausal woman have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, Follistatin. Human Activin A is a 26.0 kDa disulfide-linked homodimer of two β A chains, each containing 116 amino acid residues. *Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc. |
Catalog #: | 120-14 |
Source : | (BTI-Tn-5B1-4) High-5 Insect Cells* |
Purity : | Greater than 95% by SDS-PAGE gel and HPLC analyses. |
Endotoxin Level : | Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
Biological Activity : | The ED50 as determined by its ability to inhibit the proliferation of murine MPC-11 cells is ≤ 2 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg. |
Selected References : | Selected List of References Citing This PeproTech Product |
AA Sequence : | GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS |
PubMed Link : | Activin+AND+A+AND+human |
Country of Origin : | USA |
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| | Size A | 1μg | $80 |  | | | | Size B | 5μg | $195 | | | | | Size C | 1mg | $9800 | | | |
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| Special Sizes:
Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request. |
| Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures. |
