Aurora A KinEASE? FP-645nm FarRed Assay
型号:null    产品货号: 32-088
价格:请致电:010-57128832,18610462672
品牌: 美国

For Research Use Only; not for use in humans or as a diagnostic; 声明:本产品仅用于实验研究,不能用于人体或用于疾病诊断

omal layer, a site of pathological angiogenesis normally devoid of blood vessels, suggesting that the protein acts as a negative regulator of angiogenesis in a manner similar to that of angiopoietin-1 and angiopoietin-2. In mouse xenograft models, ANGPTL-7overexpression has been shown to lead to increased extracellular matrix components typical of a mature corneal stromal layer, as well as the reduction of tumor growth and aberrant blood vessel formation. Overexpression in human melanoma models shows a contradictory, up-regulation of endostatin, an endogenous angiostatic factor, in comparison to the down-regulation observed in mouse models. Recombinant Human ANGPTL-7 is a glycoprotein that migrates by SDS-PAGE analysis at an apparent molecular weight of 40- 50 kDa under reduced conditions, and contains 328 amino acid residues including a C-terminal His-tag. The calculated molecular weight of Recombinant Human ANGPTL-7 is 38.2 kDa.