BCL2 Gene Description B-cell CLL/lymphoma 2 Alternative Names Bcl-2 Molecular Weight 25-26 kDa Summary This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants produced by alternate splicing differ in their C-terminal ends.1

Western blot data of a siRNA transfection experiment. HeLa cells were lysed 72 hours after transfection. Cells were transfected with Transfection Reagent alone (Lane 1), 100nM ON-TARGETplus siCONTROL Non-Targeting Pool (Lane 2), or 100nM ON-TARGETplus BCL2 siRNA (Lane 3). Western blot data for GAPDH is included as a control for equal protein loading.

Special Notes
*siRNA targets Human gene product.

Product #	Description	Pkg. Size
82319	Anti-BCL2 Protein Antibody	120 µl