SRC Gene Description v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) Alternative Names ASV; SRC1; c-SRC; p60-Src Molecular Weight 60 kDa Summary This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The proteinencoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variantsencoding the same protein have been found for this gene.1

Western blot data of siRNA transfection experiment. A549 cells were lysed 72 hours after transfection. Cells were transfected with Transfection Reagent alone (Lane 1), 100nM ON-TARGETplus siCONTROL Non-Targeting Pool (Lane 2), or 100nM ON-TARGETplus SRC siRNA (Lane 3). Western blot data for GAPDH is included as a control for equal protein loading.

Special Notes
*siRNA targets Human gene product.

Product #	Description	Pkg. Size
82407	Anti-SRC Protein Antibody	100 µl