CHUK Gene Description Conserved helix-loop-helix ubiquitous kinase Alternative Names IKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha Molecular Weight 85 kDa Summary This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.1

Western blot data of a siRNA transfection experiment. A549 cells were lysed 72 hours after transfection. Cells were transfected with Transfection Reagent alone (Lane 1), 100nM ON-TARGETplus siCONTROL Non-Targeting Pool (Lane 2), or 100nM ON-TARGETplus CHUK siRNA (Lane 3). Western blot data for GAPDH is included as a control for equal protein loading.

Special Notes
*siRNA targets Human gene product.

Product #	Description	Pkg. Size
82347	Anti-CHUK Protein Antibody	100 µl