A cleavable crosslinker with an efficient photo-reactive group.

Highlights

• Sulfosuccinimidyl-(perfluoroazidobenzamido)-ethyl-1,3-dithioproprionate
• Water-soluble
• Cleavable by reducing agents
• Perfluorophenyl azide moiety photolyzes at 320 nm
• Insertion efficiency approximately 70%
• Improved stability of the singlet perfluoroaryl nitrene reactive intermediate allows high-efficiency insertion with -CH bonds vs. low efficiency ring expansion with amine nucleophiles, typical of nonfluorinated arylnitrenes
• ¹⁹F NMR can be used to monitor perfluoroaryl moiety transfer from one protein to another
• Improved photoconjugation efficiency
• Reactive groups: Sulfo-NHS ester and perfluoroaryl azide moiety
• Reactive toward: amino groups and -CH bonds

Related Products

Sulfo-SDAD – efficient photo-reactive diazirine analog of Sulfo-SFAD

Product #	Description	Pkg. Size
27719	Sulfo-SFAD	50 mg