| 人IL-6RaELISA试剂盒 英文名称： Human IL-6Ra ELISA Kit | |
| 型号:null 产品货号： EK0777 | |
| 价格:请致电：010-57128832,18610462672 | |
| 品牌: 美国 | |
产品：人IL-6RaELISA试剂盒 货号：EK0777 Description IL-6Ra (IL-6RA), also known as CD126 or IL-6R, is a type I cytokine receptor. The IL-6 receptor is a protein complex consisting of an interleukin-6 receptor subunit (IL-6R) and interleukin-6 signal transducer Glycoprotein 130. IL-6R denotes the human gene encoding this subunit. Alternatively, spliced transcript variants encoding distinct isoforms have been reported. IL-6R subunit is also shared by many other cytokines. Interleukin-6 receptor has been shown to interact with Interleukin 6 and ciliary neurotrophicFactor. Ligand binding did not appear to affect IL-6R dimerization status. IL-6R dimerization occurs both on the cell surface and in solution. ScienCells human IL-6Ra ELISA kit is based on standard sandwich enzyme-linked immune-sorbent assay technology. Human IL-6Ra-specific polyclonal antibodies are pre-coated onto 8 x 12 divisible strips. The human-specific detection monoclonal antibodies are biotinylated. The test samples and biotinylated detection antibodies are subsequently added to the wells and then washed with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex is added and unbound conjugates are washed away with PBS or TBS buffer. HRP substrate TMB is used to visualize HRP enzymatic reaction. TMB is catalyzed by HRP to produce a blue color product that changes to yellow after adding acidic stop solution. The intensity of yellow is proportional to the amount of human IL-6Ra in the sample that is captured on the strips. Product Use This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures. Storage Store at 4°C For Frequent use, at -20°C For infrequent use. Avoid multiple Freeze-thaw cycles. Shipping Shipped on gel ice Reference 1. Hoek KS, Schlegel NC, Eichhoff OM, et al.(2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665-76. 2. "Entrez Gene: IL6R interleukin 6 receptor" 3. Taga, T; Hibi M, Hirata Y, Yamasaki K, Yasukawa K, Matsuda T, Hirano T, Kishimoto T (Aug. 1989). "Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130". Cell (UNITED STATES) 58 (3): 573-81. 4. Schuster, B., Meinert, W., Rose-John, S., Kallen, K.-J. The human interleukin-6 (IL-6) receptor exists as a preformed dimer in the plasma membrane.FEBS Lett. 538: 113-116, 2003. 如需要其他产品资料请发邮件至wwwfudan@163.com索取
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