| 人TSP2ELISA试剂盒 英文名称： Human TSP2 ELISA Kit | |
| 型号:null 产品货号： EK0642 | |
| 价格:请致电：010-57128832,18610462672 | |
| 品牌: 美国 | |
产品：人TSP2ELISA试剂盒 货号：EK0642 Description Thrombospondin-2 (TSP-2) is a protein that in humans is encoded by the THBS2 gene, and is mapped to 6q27. The protein encoded by this gene belongs to the thrombospondinFamily. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown toFunction as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration. TSP-2 has been shown to interact with MMP2. ScienCells human TSP2 ELISA kit is based on standard sandwich enzyme-linked immune-sorbent assay technology. Human TSP2-specific polyclonal antibodies are pre-coated onto 8 x 12 divisible strips. The human-specific detection polyclonal antibodies are biotinylated. The test samples and biotinylated detection antibodies are subsequently added to the wells and then washed with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex is added and unbound conjugates are washed away with PBS or TBS buffer. HRP substrate TMB is used to visualize HRP enzymatic reaction. TMB is catalyzed by HRP to produce a blue color product that changes to yellow after adding acidic stop solution. The intensity of yellow is proportional to the amount of human TSP2 in the sample that is captured on the strips. Product Use This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures. Storage Store at 4°C For Frequent use, at -20°C For infrequent use. Avoid multiple Freeze-thaw cycles. Shipping Shipped on gel ice Reference 1. Hirose Y, Chiba K, Karasugi T, Nakajima M, Kawaguchi Y, Mikami Y,Furuichi T, MioF, Miyake A, Miyamoto T, Ozaki K, Takahashi A, Mizuta H, Kubo T, Kimura T, Tanaka T, Toyama Y, Ikegawa S (May 2008). "AFunctional polymorphism in THBS2 that affects alternative splicing and MMP binding is associated with lumbar-disc herniation". Am J Hum Genet 82 (5): 1122?9. 2. LaBell, T. L.; McGookey Milewicz, D. J.; Disteche, C. M.; Byers, P. H. : Thrombospondin II: partial cDNA sequence, chromosome location, and expression of a second member of the thrombospondin geneFamily in humans. Genomics 12: 421-429, 1992. 3. Bein, K; Simons M (Oct. 2000). "Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity". J. Biol. Chem. (UNITED STATES) 275 (41): 32167?73. 如需要其他产品资料请发邮件至wwwfudan@163.com索取
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