| 小鼠P-CadherinELISA试剂盒 英文名称： Mouse P-Cadherin ELISA Kit | |
| 型号:null 产品货号： EK0668 | |
| 价格:请致电：010-57128832,18610462672 | |
| 品牌: 美国 | |
产品：小鼠P-CadherinELISA试剂盒 货号：EK0668 Description P-Cadherin, also known as Cadherin-3 (CDH3), is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherinFrom the cadherin superfamily. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16. It is involved in the loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis and juvenile macular dystrophy. Cells expressing CDH3 also adhere to one another more tightly than the parental cell line. ScienCells mouse P-Cadherin ELISA kit is based on standard sandwich enzyme-linked immune-sorbent assay technology. Mouse P-Cadherin-specific polyclonal antibodies are pre-coated onto 8 x 12 divisible strips. The mouse-specific detection monoclonal antibodies are biotinylated. The test samples and biotinylated detection antibodies are subsequently added to the wells and then washed with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex is added and unbound conjugates are washed away with PBS or TBS buffer. HRP substrate TMB is used to visualize HRP enzymatic reaction. TMB is catalyzed by HRP to produce a blue color product that changes to yellow after adding acidic stop solution. The intensity of yellow is proportional to the amount of mouse P-Cadherin in the sample that is captured on the strips. Product Use This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures. Storage Store at 4°C For Frequent use, at -20°C For infrequent use. Avoid multiple Freeze-thaw cycles. Shipping Shipped on gel ice Reference 1. Kaupmann K, Becker-Follmann J, Scherer G, Jockusch H, Starzinski-Powitz A (December 1992). "The geneFor the cell adhesion molecule M-cadherin maps to mouse chromosome 8 and human chromosome 16q24.1-qter and is near the E-cadherin (uvomorulin) locus in both species". Genomics 14 (2): 488?90. 2. "Entrez Gene: CDH3 cadherin 3, type 1, P-cadherin (placental)" 3. Shimoyama, Y., Yoshida, T., Terada, M., Shimosato, Y., Abe, O., Hirohashi, S. Molecular cloning of a human Ca(2+)-dependent cell-cell adhesion molecule homologous to mouse placental cadherin: its low expression in human placental tissues. J. Cell Biol. 109: 1787-1794, 1989.
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