| 小鼠CSF1R/M-CSFRELISA试剂盒 英文名称： Mouse CSF1R/M-CSFR ELISA Kit | |
| 型号:null 产品货号： EK0808 | |
| 价格:请致电：010-57128832,18610462672 | |
| 品牌: 美国 | |
产品：小鼠CSF1R/M-CSFRELISA试剂盒 货号：EK0808 Description CSF1R (Colony stimulatingFactor 1 receptor), also known as M-CSFR and CD115, is a cell-surface protein encoded, in humans, by the CSF1R gene. The gene is located on the long arm of chromosome 5 (5q32) on the Crick (minus) strand. The encoded protein is a tyrosine kinase transmembrane receptor and a member of the CSF1/PDGF receptorFamily of tyrosine-protein kinases. The encoded protein is a single pass type I membrane protein and acts as the receptorFor colony stimulatingFactor 1 (CSF1), a cytokine which controls the production, differentiation, andFunction of macrophages. Both CSF1R and its ligand CSF1 play an important role in the development of the mammary gland and may be involved in the process of mammary gland carcinogenesis. ScienCells mouse CSF1R ELISA kit is based on standard sandwich enzyme-linked immune-sorbent assay technology. Mouse CSF1R-specific polyclonal antibodies are pre-coated onto 8 x 12 divisible strips. The mouse specific detection monoclonal antibodies are biotinylated. The test samples and biotinylated detection antibodies are subsequently added to the wells and then washed with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex is added and unbound conjugates are washed away with PBS or TBS buffer. HRP substrate TMB is used to visualize HRP enzymatic reaction. TMB is catalyzed by HRP to produce a blue color product that changes to yellow after adding acidic stop solution. The intensity of yellow is proportional to the amount of mouse CSF1R in the sample that is captured on the strips. Product Use This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures. Storage Store at 4°C For Frequent use, at -20°C For infrequent use. Avoid multiple Freeze-thaw cycles. Shipping Shipped on gel ice Reference 1. GallandF, Stefanova M, Lafage M, Birnbaum D (1992). "Localization of the 5 end of the MCF2 oncogene to human chromosome 15q15-q23". Cytogenet. Cell Genet. 60 (2): 114-6. 2. Tamimi RM, Brugge JS,Freedman ML, Miron A, Iglehart JD, Colditz GA, Hankinson SE (January 2008). 3. Pollard JW, Hennighausen L (September 1994). "Colony stimulatingFactor 1 is requiredFor mammary gland development during pregnancy". Proc. Natl. Acad. Sci. U.S.A. 91 (20): 9312-6. 4. Sapi E (January 2004). "The role of CSF-1 in normal physiology of mammary gland and breast cancer: an update". Exp. Biol. Med. (Maywood) 229 (1): 1-11.
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