- Product Description:
- Homo sapiens ribonuclease III, nuclear (RNASEN), mRNA.
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Note:
- Position of the Chimera RNAi.
-
 - Gene Alias:
- DROSHA,ETOHI2,HSA242976,RANSE3L,RN3,RNASE3L
- Gene Description:
- ribonuclease type III, nuclear
- Gene Summary:
- Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003 [PubMed 14508493]).[supplied by OMIM
- Other Designations:
- drosha, double-stranded RNA-specific endoribonuclease,drosha, ribonuclease type III,nuclear RNase III Drosha,putative protein p241 which interacts with transcription factor Sp1,putative ribonuclease III,ribonuclease III, nuclear
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