英文名称： FABP1 Pre-design Chimera RNAi
- Specification
- Product Description:
- Homo sapiens fatty acid binding protein 1, liver (FABP1), mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_001443
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 2168
- Gene Name:
- FABP1
- Gene Alias:
- FABPL,L-FABP
- Gene Description:
- fatty acid binding protein 1, liver
- Omim ID:
- 134650
- Gene Ontology:
- Hyperlink
- Gene Summary:
- FABP1 encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP1 and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq
- Other Designations:
- Fatty acid-binding protein, liver
- Gene Pathway
- Related Disease
- Atherosclerosis
- Body Weight
- Cardiovascular Diseases
- Cerebral Infarction
- Diabetes Mellitus
- Diabetes Mellitus, Type 2
- Dyslipidemias
- Edema
- Genetic Predisposition to Disease
- Hyperlipoproteinemias
- Hypertriglyceridemia
- *** Resistance
- Intracranial Arteriosclerosis
- Metabolic Syndrome X
- Myocardial Infarction
- Obesity
- Stroke