usaBrand,null 产品货号： 6601SItem#, SignalSilence p38δ MAPK siRNA II<br>英文名称： SignalSilence p38δ MAPK siRNA II

SignalSilence p38δ MAPK siRNA II
英文名称： SignalSilence p38δ MAPK siRNA II

型号:null 产品货号： 6601S

价格:请致电：010-57128832,18610462672

品牌: usa

MAP Kinase Signaling

subunit (AP1S1), transcript variant 2, mRNA.

Reactivity:
Human

Storage Instruction:
Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.

Supplied Product:
DEPC water

Target Refseq:
NM_057089

Note:
Position of the Chimera RNAi.
The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence.

Publication Reference

1.
dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.

2.
Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.

3.
Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.

4.
siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.

Applications

RNAi Knockdown

Application Image

RNAi Knockdown

Gene Information

Entrez GeneID:
1174

Gene Name:
AP1S1

Gene Alias:
AP19,CLAPS1,FLJ92436,SIGMA1A,WUGSC:H_DJ0747G18.2

Gene Description:
adaptor-related protein complex 1, sigma 1 subunit

Omim ID:
603531

Gene Ontology:
Hyperlink

Gene Summary:
The protein encoded by this gene is part of the clathrin coat assembly complex which links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. This protein, as well as beta-prime-adaptin, gamma-adaptin, and the medium (mu) chain AP47, form the AP-1 assembly protein complex located at the Golgi vesicle. [provided by RefSeq

Other Designations:
AP-1 complex subunit sigma-1A,HA1 19 kDa subunit,clathrin assembly protein complex 1 sigma-1A small chain,clathrin coat assembly protein AP19,clathrin-associated/assembly/adaptor protein, small 1 (19kD),golgi adaptor HA1/AP1 adaptin sigma-1A subunit,sigma

Gene Pathway

Lysosome

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