usaBrand,null 产品货号： 7865SItem#, SignalSilence PEA-15 siRNA II<br>英文名称： SignalSilence PEA-15 siRNA II

SignalSilence PEA-15 siRNA II
英文名称： SignalSilence PEA-15 siRNA II

型号:null 产品货号： 7865S

价格:请致电：010-57128832,18610462672

品牌: usa

Apoptosis

ontent">Homo sapiens SRY (sex determining region Y)-box 3 (SOX3), mRNA.

Reactivity:
Human

Storage Instruction:
Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.

Supplied Product:
DEPC water

Target Refseq:
NM_005634

Note:
Position of the Chimera RNAi.

Publication Reference

1.
dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.

2.
Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.

3.
Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.

4.
siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.

Applications

RNAi Knockdown

Application Image

RNAi Knockdown

Gene Information

Entrez GeneID:
6658

Gene Name:
SOX3

Gene Alias:
GHDX,MRGH,PHP,PHPX,SOXB

Gene Description:
SRY (sex determining region Y)-box 3

Omim ID:
300123, 313430

Gene Ontology:
Hyperlink

Gene Summary:
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency. [provided by RefSeq

Other Designations:
OTTHUMP00000024166,transcription factor SOX-3

Related Disease

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