PIK3CA/CEN3q FISH Probe
英文名称： PIK3CA/CEN3q FISH Probe
型号:null    产品货号： FG0073
价格:请致电：010-57128832,18610462672
品牌: 台湾

  • Specification
  • Product Description:
  • Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)
  • Storage Instruction:
  • Store at 4°C in the dark.
  • Quality Control Testing:
  • Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    QC Testing of FG0073
  • Supplied Product:
  • DAPI Counterstain (1500 ng/mL ) 250 uL
  • Note:
  • Hybridization position of the probes on the chromosome:

  • Probe 1:
        Size:
        Fluorophore:
        Location:
  • PIK3CA
    Approximately 280kb
    Texas Red
    3q26.32
  • Probe 2:
        Size:
        Fluorophore:
        Location:
  • CEN3q
    Approximately 500kb
    FITC
    3q12.1
  • Probe Gap:
  • The gap between two probes is approximately 82,800 kb.
  • Origin:
  • Human
  • Source:
  • Genomic DNA
  • Notice:
  • We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Human lung adenosquamous cell carcinoma (FFPE) stained with PIK3CA/CEN3q FISH Probe. Human lung adenosquamous cell carcinoma showed PIK3CA gene amplification.
  • Protocol Download
  • Application Image
  • Fluorescent In Situ Hybridization (Cell)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5290
  • Gene Name:
  • PIK3CA
  • Gene Alias:
  • MGC142161,MGC142163,PI3K,p110-alpha
  • Gene Description:
  • phosphoinositide-3-kinase, catalytic, alpha polypeptide
  • Gene Summary:
  • Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. [provided by RefSeq
  • Other Designations:
  • PI3-kinase p110 subunit alpha,PtdIns-3-kinase p110,phosphatidylinositol 3-kinase, catalytic, 110-KD, alpha,phosphatidylinositol 3-kinase, catalytic, alpha polypeptide,phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, alpha isoform
  • Related Disease

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