- Product Description:
- Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL) 250 uL
- Notice:
- We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
- Regulation Status:
- For research use only (RUO)
- Fluorescent In Situ Hybridization (Cell)
- Gene Alias:
- B-RAF1,BRAF1,FLJ95109,MGC126806,MGC138284,RAFB1
- Gene Description:
- v-raf murine sarcoma viral oncogene homolog B1
- Gene Summary:
- This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq
- Other Designations:
- 94 kDa B-raf protein,B-Raf proto-oncogene serine/threonine-protein kinase (p94),Murine sarcoma viral (v-raf) oncogene homolog B1
- Abnormalities, Multiple
- Adenocarcinoma
- Adenocarcinoma, Follicular
- Adenocarcinoma, Mucinous
- Adenocarcinoma, Papillary
- Adenoma
- Adenoma, Oxyphilic
- Adrenal Cortex Neoplasms
- Alcoholism
- Articulation Disorders
- Astrocytoma
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Basal Cell
- Carcinoma, Medullary
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Papillary
- Carcinoma, Papillary, Follicular
- Carcinoma, Squamous Cell
- Carcinoma, Transitional Cell
- Cell Transformation, Neoplastic
- Chromosomal Instability
- Chromosome Aberrations
- Cognition
- Cognition Disorders
- Colon cancer
- Colonic Neoplasms
- Colonic Polyps
- Colorectal Neoplasms
- Colorectal Neoplasms, Hereditary Nonpolyposis
- Common Bile Duct Neoplasms
- Craniofacial Abnormalities
- Cystadenocarcinoma, Mucinous
- Cystadenocarcinoma, Serous
- Cystadenoma, Serous
- Developmental Disabilities
- Dilatation, Pathologic
- Disease Progression
- Diseases in Twins
- Dyslexia, Acquired
- Ectodermal Dysplasia
- Endometrial Hyperplasia
- Endometrial Neoplasms
- Endometriosis
- Eosinophilia
- Esophageal Neoplasms
- Gastrointestinal Stromal Tumors
- Genetic Predisposition to Disease
- Glioma
- Goiter
- Goiter, Nodular
- Hashimoto Disease
- Head and Neck Neoplasms
- Hearing
- Heart Defects, Congenital
- Hyperpigmentation
- Hyperplasia
- Immunologic Deficiency Syndromes
- Language Disorders
- Liver Neoplasms
- Lung Neoplasms
- Lymphatic Metastasis
- Lymphoma, Non-Hodgkin
- Malignant melanoma
- Melanoma
- Memory
- Microsatellite Instability
- Motor Skills
- Nasopharyngeal Neoplasms
- Necrosis
- Neoplasm Invasiveness
- Neoplasm Metastasis
- Neoplasm Recurrence, Local
- Neoplasms
- Neoplasms, Germ Cell and Embryonal
- Neoplasms, Glandular and Epithelial
- Neoplasms, Multiple Primary
- Neoplasms, Radiation-Induced
- Nerve Sheath Neoplasms
- Neurofibromatosis
- Neurofibromatosis 1
- Nevus
- Nevus, Pigmented
- Noonan Syndrome
- Obesity
- Ovarian cancer
- Ovarian Neoplasms
- Pancreatic cancer
- Pancreatic Neoplasms
- Papillomavirus Infections
- Precancerous Conditions
- Prostatic Neoplasms
- Ras oncogene
- Rectal Neoplasms
- Recurrence
- Salivary Gland Neoplasms
- Skin Neoplasms
- Stomach Neoplasms
- Syndrome
- Testicular Neoplasms
- Thyroid Diseases
- Thyroid Neoplasms
- Thyroid Nodule
- Thyroiditis, Autoimmune
- Tobacco Use Disorder
- Urinary Bladder Neoplasms
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