英文名称： HEY1/NCOA2 DY Translocation FISH Probe
- Specification
- Product Description:
- Labeled FISH probes for identification of gene translocation using Fluorescent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Quality Control Testing:
- Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Note:
- Hybridization position of the probes on the chromosome:
-
- Probe 1:
Size:
Fluorophore:
Location: - NCOA2
Approximately 1300kb
Texas Red
8q13.3
- Probe 2:
Size:
Fluorophore:
Location: - HEY1
Approximately 1250kb
FITC
8q21.13
- Probe Gap:
- The gap between two probes is approximately 8,200 kb.
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Huma lung, adenosquamous cell carcinoma (FFPE) stained with HEY1/NCOA2 DY Translocation FISH Probe. Human lung cancer showed no HEY/NCOA2 DY Translocation.
- Protocol Download
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Human hemangiopericytoma (FFPE) stained with HEY1/NCOA2 DY Translocation FISH Probe. Human hemangiopericytoma showed no HEY1/NCOA2 DY translocation.
- Protocol Download
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Human mesenchymal chondrosarcoma (FFPE) stained with HEY1/NCOA2 DY Translocation FISH Probe. Human mesenchymal chondrosarcoma showed no HEY1/NCOA2 DY translocation.
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Entrez GeneID:
- 10499
- Gene Name:
- NCOA2
- Gene Alias:
- GRIP1,KAT13C,MGC138808,NCoA-2,TIF2,bHLHe75
- Gene Description:
- nuclear receptor coactivator 2
- Omim ID:
- 601993
- Gene Ontology:
- Hyperlink
- Other Designations:
- glucocorticoid receptor-interacting protein-1
- Entrez GeneID:
- 23462
- Gene Name:
- HEY1
- Gene Alias:
- BHLHb31,CHF2,HERP2,HESR1,HRT-1,MGC1274,OAF1
- Gene Description:
- hairy/enhancer-of-split related with YRPW motif 1
- Omim ID:
- 602953
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq
- Other Designations:
- HES-related repressor protein 2,basic helix-loop-helix protein OAF1,cardiovascular helix-loop-helix factor 2,hairy-related transcription factor 1