Sulindac sulfone
Sulindac sulfone
S1438 -≥97% (TLC), (solid or powder)
DOWNLOAD MSDS (PDF) 
别名: (Z)-5-Fluoro-2-methyl-1-[p-(methylsulfonyl)benzylidene]indene-3-acetic acid
    
    
CAS号: 59864-04-9
    
    
    
经验分子式（希尔表示法）: C20H17FO4S
    
    
    
分子量: 372.41
    
    
    
MDL number: MFCD01317811
    
    
    
PubChem Substance ID: 24278693
    
性质
    
        
            
相关类型
            
Anti-inflammatory, Antitumor Agents, Arachidonic Acid Cascade, Bioactive Small Molecules, Cancer Research,            
            
Cell Biology, Chemopreventive Agents, Enzyme Inhibitors, Lipids in Cell Signaling, S
            more...
            
        
        
            
assay
            
≥97% (TLC)
        
        
            
form
            
(solid or powder)
        
        
            
color
            
, Light Yellow to Dark Yellow
        
        
            
solubility
            
DMSO: >25 mg/mL
        
        
            
 
            
ethanol: soluble3 mg/mL (warm)
        
        
            
 
            
acetone: soluble5 mg (plus 0.1 ml)
        
    
 
描述
Biochem/physiol Actions
Metabolite of sulindac that inhibits cell growth by inducing apoptosis independently of cyclooxygenase inhibition. Inhibits the development and induces regression of premalignant adenomatous polyps.