Source: Rabbit Muscle

I.U.B.: 1.1.1.27

Mammalian lactate dehydrogenases (LDH) exist as five tetrameric isozymes composed of combinations of two different subunits. The H subunit predominates in heart muscle, which is geared for aerobic oxidation of pyruvate. The M subunit predominates in skeletal muscle and is concerned more with anaerobic metabolism and pyruvate reduction.

Unit Definition: One Unit oxidizes one micromole of NADH per minute at 25°C, pH 7.3