Source: Porcine Heart Mitochondria

I.U.B.: 1.1.1.37 

Malate dehydrogenase (MDH) catalyzes the interconversion of L-malate and oxaloacetate using nicotinamide adenine dinucleotide as a coenzyme. Malate dehydrogenase is found in all eukaryotic cells as two isozymes: mitochondrial (membrane bound) (M-MDH) and cytoplasmic (soluble) (S-MDH). Both forms have molecular weights of approximately 70,000 daltons and a pH optimum of 7.4.

Unit Definition: One Unit oxidizes one micromole of NADH per minute at 25°C, pH 7.4