Recombinant Rat SCF

产品编号:

400-22

别名:

Stem Cell Factor, c-Kit Ligand, Mast Cell Growth Factor (MGF), Steel Factor

描述:

Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant rat SCF is an 18.4 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.

氨基酸序列:

MQEICRNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV THLSVSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVAC MEENAPKNVK ESLKKPETRN FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA

来源:

E.coli

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

Determined by the dose-dependent stimulation of the proliferation of the human TF-1 cells. The expected ED₅₀ for this effect is 20 - 40 ng/ml.

交叉反应:

Human, Mouse