小鼠小脑星形胶质细胞 英文名称: MA-c |
型号:null 产品货号: M1810 |
价格:请致电:010-57128832,18610462672 |
品牌: 美国sciencell |
北京裕恒丰科技有限公司,已成功代理美国Sciencell公司细胞生物学产品十余年。多年来,裕恒丰一直秉承信誉至上的原则,在点滴中慢慢地提升企业信誉,树立企业形象,我们始终以热心的服务和专业的技术支持,为广大科研工作者提供了优质的细胞及分子生物学产品。在未来的发展中,我们将继续努力打造企业品牌,北京裕恒丰不仅希望您能聆听到我们的心声,更期待您能亲自体验我们的服务,北京裕恒丰欢迎您的光临。 温馨提示:ScienCell从不提供永生化细胞,所有细胞均为正常原代细胞。ScienCell在中国地区不销售分装后的细胞。如预购买产品请登陆ScienCell唯一官网(www.sciencellonline.com)寻找正规代理商,以确保您的实验顺利进行。 小鼠小脑星形胶质细胞 货号M1810 细胞来源 Astrocytes are the major cell type in the mammalian brain. They provide a variety of supportive functions to their partner neurons in the central nervous system (CNS), such as neuronal guidance during development, nutritional and metabolic support throughout life [1]. Astrocytes have also been implicated in various pathological processes [2]. Impairment of normal astrocyte functions during stroke and other insults can critically influence neuron survival. Long-term recovery after brain injury, through neurite outgrowth, synaptic plasticity, or neuron regeneration, is also influenced by astrocyte surface molecule expression and trophic factor release [3]. Numerous studies have demonstrated that astrocytes are among the most functionally diverse group of cells in the CNS [4]. Much of what we have learned about astrocytes is from in vitro studies and astrocyte culture is a useful tool for exploring the diverse properties of this cell type. MA-c from ScienCell Research Laboratories are isolated from postnatal day 8 mouse cerebellum. MA-c are cryopreserved as primary cultures and delivered frozen. Each vial contains >5 x 105 cells in 1 ml volume. MA-c are characterized by immunofluorescence with antibody specific to GFAP. MA-c are negative for mycoplasma, bacteria, yeast, and fungi. MA-c are guaranteed to further expand for 5 population doublings under the conditions provided by ScienCell Research Laboratories. 推荐培养基 It is recommended to use Astrocyte Medium-animal (AM-a, Cat. #1831) for culturing MA-c in vitro. 参考文献 [1] Rudge JS. (1993) “Astrocyte-derived neurotrophic factors.” In Murphy S, Astrocytes: Pharmacology and Function (pp 267-94). San Diego: Academic Press, Inc. [2] van der Laan LJ, De Groot CJ, Elices MJ, Dijkstra CD. (1997) “Extracellular matrix proteins expressed by human adult astrocytes in vivo and in vitro: an astrocyte surface protein containing the CS1 domain contributes to binding of lymphoblasts.” J Neurosci Res. 50: 539-48. [3] Chen Y, Swanson RA. (2003) “Astrocytes and brain injury.” J Cereb Blood Flow Metab. 23: 137-49. [4] Shao Y, McCarhy KD. (1994) “Plasticity of astrocytes.” Glia. 11: 147-55. |