小鼠肺成纤维细胞 英文名称: MPF |
型号:null 产品货号: M3300-57 |
价格:请致电:010-57128832,18610462672 |
品牌: 美国sciencell |
北京裕恒丰科技有限公司,已成功代理美国Sciencell公司细胞生物学产品十余年。多年来,裕恒丰一直秉承信誉至上的原则,在点滴中慢慢地提升企业信誉,树立企业形象,我们始终以热心的服务和专业的技术支持,为广大科研工作者提供了优质的细胞及分子生物学产品。在未来的发展中,我们将继续努力打造企业品牌,北京裕恒丰不仅希望您能聆听到我们的心声,更期待您能亲自体验我们的服务,北京裕恒丰欢迎您的光临。 温馨提示:ScienCell从不提供永生化细胞,所有细胞均为正常原代细胞。ScienCell在中国地区不销售分装后的细胞。如预购买产品请登陆ScienCell唯一官网(www.sciencellonline.com)寻找正规代理商,以确保您的实验顺利进行。
小鼠肺成纤维细胞 货号M3300-57 细胞来源 The most abundant cell type in the lung interstitium is the fibroblast. These fibroblasts resemble ordinary fibroblasts, but also possess some distinguishing features such as long, branching processes and gap junctions. Pulmonary fibroblasts function to produce type III collagen, elastin, and proteoglycans of the extracellular matrix of the alveolar septa. They play an important role in the repair and remodeling processes following tissue damage. The controlled accumulation of fibroblasts to sites of inflammation is crucial to effective tissue repair after injury [1]. An inadequate or an excessive accumulation of fibroblasts can result in abnormal tissue function. For example, excess proliferation of fibroblasts contributes to adventitial thickening observed during the development of hypoxia-induced pulmonary hypertension [2]. MPF from ScienCell Research Laboratories are isolated from postnatal day 2 C57BL/6 mouse lung. MPF are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 105 cells in 1 ml volume. MPF are characterized by immunofluorescence with antibody specific to fibronectin. MPF are negative for mycoplasma, bacteria, yeast, and fungi. HPF are guaranteed to further expand for 5 population doublings under the conditions provided by ScienCell Research Laboratories. 推荐培养基 It is recommended to use Fibroblast Medium (FM, Cat. #2301) for culturing MPF in vitro. 参考文献 [1] Kuwano K, Hagimoto N, Hara N. (2001) “Molecular mechanisms of pulmonary fibrosis and current treatment.” Curr Mol Med. 1: 551-73. [2] Das M, Dempsey EC, Reeves JT, Stenmark KR. (2002) “Selective expansion of fibroblast subpopulations from pulmonary artery adventitia in response to hypoxia.” Am J Physiol Lung Cell Mol Physiol. 282: L976- |