Anti-ATM (Q2442P) Mouse Monoclonal Antibody
英文名称： Anti-ATM (Q2442P) Mouse Monoclonal Antibody
型号:null    抗体货号： 26142
价格:请致电：010-57128832,18610462672
品牌: 美国    产品商标: neweastbio

 

ATM (Q2442P) [26142]
[100 µL]		  

Catalog Number:  26142
Gene Symbol:  ATM
Description:   Anti-ATM (Q2442P) Mouse Monoclonal Antibody
Background:   Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activity of ATM protein is under tight control, and mutation of ATM can cause disease such as Ataxia telangiectasia (AT) and cancers.
Immunogen:   A synthetic peptide from the internal region of ATM which includes the mutation of Q2442P, human origin.
Applications:   ELISA, WB, IHC
Recommended Dilutions:   
ELISA: 1:1000-1:5000 
WB: 1:100-1:1000 
IHC: 1:50-1:500
Concentration:   1 mg/ml
Host:   Mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   
Purity:   Purified from ascites
Storage buffer:
Preservative:  no
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Recognizes ATM (Q2442P), but not wild type ATM protein from vertebrates.
Storage Conditions:   Store at -20°C. Avoid freeze / thaw cycles
 
Western blot:  
Western blot analysis of recombinant ATM (Q2442P) and wildtype proteins. Purified His-tagged ATM (Q2442P) protein (amino acids 2400-3056, lane 2) and corresponding wild type protein (lane 1) were blotted with anti-ATM (Q2442P) mouse monoclonal antibody (Cat. #26142).