Anti- Gαq sub-family Mouse Monoclonal Antibody
英文名称: Anti-Gαq sub-family Mouse Monoclonal Antibody
型号:null    抗体货号: 26060
价格:请致电:010-57128832,18610462672
品牌: 美国    产品商标: neweastbio

Gαq sub-family [26060]
[100 µL]
 

Catalog Number:  26060
Gene Symbol:  GNAQ
Description:   Anti-Gαq sub-family Mouse Monoclonal Antibody
Background:   Heterotrimeric G proteins are essential cellular signal transducers. Members (Gαq, Gα11, Gα14, Gα15 and Gα16) of the Gq sub-family of G proteins are known to stimulate phospholipase C. Other biochemical and physiological functions of Gαq sub-family are being explored.
Immunogen:   A synthetic peptide common to all members of Gαq subfamily.
Applications:   ELISA, WB, IHC, IP
Recommended Dilutions:   
ELISA 1:1000-1:5000
WB 1:100-1:2000
IHC 1:50-1:100
Concentration:   1 mg/ml
Host:   mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   IgG
Purity:   Purified from ascites
Storage buffer:
Preservative:  no
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  q subfamily antibody recognizes all members of the Gq subfamily of vertebrates.
Storage Conditions:  Store at -20°C. Avoid freeze / thaw cycles
 
Western blot:  
Western blot of Gαq proteins with anti-Gαq sub-family mouse monoclonal antibody (Cat # 26060).

 

Publications:
1.  Muscarinic acetylcholine receptor-mediated activation of G(q) in rat brain membranes determined by guanosine-5'-O-(3-[35S]thio)triphosphate ([35S]GTPgammaS) binding using an anti-G protein scintillation proximity assay
    J Neural Transm. 2012 May;119(5):525-32

 

b>   Rapid actions of xenoestrogens disrupt normal estrogenic signaling
     Steroids Volume 81, March 2014, Pages 36–42 6.   Neuronal NF1/RAS regulation of cyclic AMP requires atypical PKC activation
     Hum. Mol. Genet. (2014)