Catalog Number: 21202 |
Gene Symbol: ERBB2/HER2/Neu |
Description: Anti-ErbB2 Rabbit Polyclonal Antibody |
Background: The ErbB family is composed of four plasma membrane-bound receptor tyrosine kinases. Amplification or over-expression of the ERBB2 gene occurs in approximately 30% of breast cancers. HER2 is encoded by ERBB2, a known proto-oncogene located at the long arm of human chromosome 17(17q21-q22). HER2 proteins have been shown to form clusters in cell membranes that may play a role in tumorigenesis. |
Immunogen: A synthetic peptide from the central of ErbB2 protein. |
Applications: ELISA, WB, IHC |
Recommended Dilutions: ELISA: 1:500-1:5000 WB: 1:200-1:2000 IHC: 1:20-1:200 |
Concentration: 0.2 mg/ml |
Host: Rabbit |
Format: Liquid |
Clonality: Polyclonal |
Isotype: |
Purity: Purified from serum |
Storage buffer: |
Preservative: no |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Recognizes ErbB2 of vertebrates. |
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles. |
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Western blot: |