| Catalog Number: 26135 |
| Gene Symbol: BAG1, BAG-1, HAP, RAP46 |
| Description: Anti-Bag1 Mouse Monoclonal Antibody |
| Background: BAG family molecular chaperone regulator 1 is a protein that is encoded by the BAG1 gene. It binds to oncogene BCL2, by which enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. BAG gene has been implicated in age related neurodegenerative diseases as Alzheimer's. It has been demonstrated that BAG1 and BAG3 regulate the proteasomal and lysosomal protein elimination pathways, respectively. |
| Immunogen: Purified recombinant Bag1 protein, human origin. |
| Applications: ELISA, WB, IHC |
Recommended Dilutions:
ELISA: 1:500-1:5000
WB: 1:500-1:2000
IHC: 1:50-100 |
| Concentration: 1 mg/ml |
| Host: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: |
| Purity: Purified from ascites |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes Bag1 from vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
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| Western blot: |
