Anti-Cdc42+Rac1+RhoA Rabbit Polyclonal Antibody
英文名称：  Anti-Cdc42+Rac1+RhoA Rabbit Polyclonal Antibody
型号:null    抗体货号： 21035
价格:请致电：010-57128832,18610462672
品牌: 美国    产品商标: neweastbio

 

Rho family pan antibody (Cdc42+Rac1+RhoA) [21035]
[100 µL]		  
Catalog Number:  21035
Gene Symbol:  CDC42+RAC1+RHOA
Description:   Anti-Cdc42+Rac1+RhoA Rabbit Polyclonal Antibody
Background:   Small GTPases are a super-family of cellular signaling regulators. The Rho sub-family GTPases regulate cell motility, cell division, and gene transcription.
Immunogen:   A synthetic peptide from the N -terminal region common among Cdc42, Rac1, and RhoA.
Applications:   ELISA, WB, IHC
Recommended Dilutions:   ELISA 1:100-1:5000
WB 1:100-1:2000
IHC 1:100-1:1000
Concentration:   0.2 mg/ml
Host:   Rabbit
Format:   Liquid
Clonality:   Polyclonal
Isotype:   IgG
Purity:   Purified from serum
Storage buffer:
Preservative:  no
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Rho family pan antibody recognizes Cdc42, Rac1, and RhoA from vertebrates.
Storage Conditions:  Store at -20°C. Avoid freeze / thaw cycles
Download Datasheet:  
Western blot:  
EC-1 whole-cell lysate was used for Western blot with the polyclonal Rho family pan antibody (cat # 21035).
Publications:
1.  Vibrio parahaemolyticus Effector Proteins Suppress Inflammasome Activation by Interfering with Host Autophagy Signaling
    PLoS Pathog. 2013 Jan;9(1):e1003142
2.  Interferon gamma induces actin polymerization, Rac1 activation and down regulates phagocytosis in human monocytic cells
    Cytokine. 2012 Jan;57(1):158-68
3.  Invadopodia and rolling-type motility are specific features of highly invasive p190bcr-abl leukemic cells
    European Journal of Cell Biology Volume 91, Issues 11–12, November–December 2012, Pages 978–987
4.  Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex
    J Cell Biol. 2012 Aug 20;198(4):677-93
5.  Polarized migration of lymphatic endothelial cells is critically dependent on podoplanin regulation of Cdc42
    Am J Physiol Lung Cell Mol Physiol. 2011 Jan;300(1):L32-42
6.  The Aarskog-Scott Syndrome Protein Fgd1 Regulates Podosome Formation and Extracellular Matrix Remodeling in Transforming Growth Factor beta-Stimulated Aortic Endothelial Cells
    Mol Cell Biol. 2011 Nov;31(22):4430-41
7.  MMP-9 and CXCL8/IL-8 Are Potential Therapeutic Targets in Epidermolysis Bullosa Simplex
    PLoS One. 2013 Jul 19;8(7):e70123
8.  p21-Activated Kinase (PAK) Regulates Cytoskeletal Reorganization and Directional Migration in Human Neutrophils
    PLoS One. 2013 Sep 3;8(9):e73063
9.  The Cdc42 Guanine Nucleotide Exchange Factor FGD6 Coordinates Cell Polarity and Endosomal Membrane Recycling in Osteoclasts
    J Biol Chem. 2014 Jun 27;289(26):18347-59
10.  Cdc42 Inhibitor and Uses Thereof
    United States Patent Application 20140194451
11.  The α4 Nicotinic Receptor Promotes CD4+ T-Cell Proliferation and a Helper T-Cell Immune Response
    Molecular Pharmacology January 2014 vol. 85 no. 1 50-61