目录号 规格 价格 说明书下载 C574A 2μg 400元 C574B 10μg 1800元 C574C 50μg 4500元

CMRF35-like molecule 8, also known as CD300 antigen-like family member A, Immunoglobulin superfamily member 12, Inhibitory receptor protein 60, CD300A, CMRF35H and IGSF12, is a Single-pass type I membrane protein which Belongs to the CD300 family. CD300A consists of a 163 amino acid (aa) extracellular domain (ECD) with one Ig-like V- type domain, a 21 aa transmembrane segment, and a 98 aa cytoplasmic domain with tyrosine residues. CD300A is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. ·Description Novoprotein Recombinant Human LMIR1/CD300A produced by mammalian cells expression system.Target protein is expressed with sequence (Leu18-Gln178) of Human cd300a (Uniprot #Q9UGN4) fused with a polyhistidine tag at the C-terminus. ·Quality Control Purity: Greater than 90.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.   Endotoxin:Less than 0.1ng/μg (1EU/μg) of LMIR1/CD300A (Human)   ·Formulation   Novoprotein Recombinant Human CD300A was lyophilized at 1mg/ml in 20mM PBS. ·Reconstitution We recommend a quick spin followed by reconstitution of Novoprotein Recombinant Human CD300A in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to working solutions. ·Storage Lyophilized Recombinant Human CD300A although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Recombinant Human CD300A should be stored at 4°C between 2-7 days and aliquots of reconstituted samples are stable up to 3 months below -18°C for future use.   Please avoid freeze-thaw cycles.