目录号 规格 价格 说明书下载 C585A 2μg 400元 C585B 10μg 1800元 C585C 50μg 4500元

FHR1 (Complement Factor H-related protein 1), also known as FHR-1, H factor-like protein 1, H-factor-like 1 and H36, is a 43 kDa, secreted member of the factor H family of glycoproteins. The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. FHR1 is produced by hepatocytes and circulates as two differentially glycosylated isoforms (37 kDa and 43 kDa). Mature human FHR1 is 312 amino acids (aa) in length. It contains five, approximately 60 aa SCRs that basically constitute the entire molecule. FHR1 may play a role in complement regulation, lipid metabolism and lipoprotein complexes that bind PMNs to LPS. ·Description Novoprotein Recombinant Human Complement Factor H-related 1/CFHR1 produced by mammalian cells expression system.Target protein is expressed with sequence (Glu19-Arg330) of Human cfhr1 (Uniprot #Q03591) fused with a polyhistidine tag at the C-terminus. ·Quality Control Purity: Greater than 90.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.   Endotoxin:Less than 0.1ng/μg (1EU/μg) of Complement Factor H-related 1/CFHR1 (Human)   ·Formulation   Novoprotein Recombinant Human CFHR1 was lyophilized at 1mg/ml in 20mM PBS. ·Reconstitution We recommend a quick spin followed by reconstitution of Novoprotein Recombinant Human CFHR1 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to working solutions. ·Storage Lyophilized Recombinant Human CFHR1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Recombinant Human CFHR1 should be stored at 4°C between 2-7 days and aliquots of reconstituted samples are stable up to 3 months below -18°C for future use.   Please avoid freeze-thaw cycles.