目录号 规格 价格 说明书下载 C573A 2μg 400元 C573B 10μg 1800元 C573C 50μg 4500元

T-cell surface glycoprotein CD1c, is a single-pass type I membrane protein which contains 1 Ig-like (immunoglobulin-like) domain. CD1c is expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues. During CD1c synthesis and maturation, CD1 family members bind endogenous lipids that are replaced by lipid or glycolipid antigens when the proteins are internalized and pass through endosomes or lysosomes, before trafficking back to the cell surface. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. Antigen-presenting protein can binds self and non-self lipid and glycolipid antigens, presents them to T-cell receptors on natural killer T-cells. ·Description Novoprotein Recombinant Human CD1c/BDCA-1 produced by mammalian cells expression system.Target protein is expressed with sequence (Asn20-Met302) of Human cd1c (Uniprot #P29017) fused with a polyhistidine tag at the C-terminus. ·Quality Control Purity: Greater than 90.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.   Endotoxin:Less than 0.1ng/μg (1EU/μg) of CD1c/BDCA-1 (Human)   ·Formulation   Novoprotein Recombinant Human CD1C was lyophilized at 1mg/ml in 20mM PBS. ·Reconstitution We recommend a quick spin followed by reconstitution of Novoprotein Recombinant Human CD1C in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to working solutions. ·Storage Lyophilized Recombinant Human CD1C although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Recombinant Human CD1C should be stored at 4°C between 2-7 days and aliquots of reconstituted samples are stable up to 3 months below -18°C for future use.   Please avoid freeze-thaw cycles.