分子量:76 kDa纯度:>92% as determined by SDS-PAGE.内毒素:Less than 1.0 EU per μg of the Human Transferrin R, His Tag by the LAL method.Buffer:PBS, pH7.4生物活性:Measured by its binding ability in a functional ELISA. Immobilized Human Transferrin R, His Tag at 10 μg/mL ( 100 μl/well ) can bind human Transferrin. The EC50 of human Transferrin is  6.4 ng/mL.产品特性:Human Transferrin R, His Tag is fused with a polyhistidine tag at the N-terminus, and has a calculated MW of 76 kDa. The predicted N-terminus is Cys 89. The reducing (R) protein migrates as 80-85 kDa in SDS-PAGE  due to glycosylation.产品背景:CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE. 

SDS-PAGE