Arf6ProteinΔ12Q67Lmutant
英文名称: Arf6Protein Δ12 Q67L mutant
型号:null    产品货号: 10125
价格:请致电:010-57128832,18610462672
品牌: 美国
试剂级别: 试剂级

 

Arf6 Protein Δ12 Q67L mutant [10125]
[10 µg]
 
Catalog Number:  10125
Product Name:  Arf6 Protein Δ12 Q67L mutant
Synonyms:  ADP-ribosylation factor 6
Source:    Human, recombinant, His6-tag
Expression Host:   E. coli
Molecular Weight:   20 kDa
Purity:    >95% by SDS-PAGE
Introduction:   Arf6 is a member of the ARF super-family. ARF genes encode small GTPases that increase the ADP-ribosyltransferase activity of cholera toxin and are critical for vesicular trafficking as activators of phospholipase D. Arf6 regulates membrane trafficking and the actin cytoskeketon at the plasma membrane and functions as a regulatory molecule of phagocytosis.
Amino Acid Sequence   (1-175, Δ12, Q67L)
MGKVLSKIFGN-EMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGL 
DKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHE 
IQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS
Properties
Physical Appearance (form):   Dissolved in 20mM Tris-HCl, pH8.0, 150mM NaCl.
Physical Appearance (form):  White or clear
Concentration:  1mg/mL
Storage:   -80°C
References:  
1. Geppert, M. et al., Nature 387: 810-814, 1997. 
2. Giovedi, S. et al., J. Biol. Chem. 279: 43769-43779, 2004. 
3. Huang, Y.-Y. et al., Proc. Nat. Acad. Sci. 102: 9365-9370, 2005. 
4. Kapfhamer, D. et al., Nature Genet. 32: 290-295, 2002. 
5. Rousseau-Merck, M. F. et al., Genomics 5: 694-698, 1989. 
6. Rousseau-Merck, M. F. et al., Cytogenet. Cell Genet. 51: 1070-only, 1989. 
7. Sullivan, M. et al., Cell. Signal. 11: 735-742, 1999. 
8. Trask, B. et al., Genomics 15: 133-145, 1993. 
9. Zahraoui, A. et al., J. Biol. Chem. 264: 12394-12401, 1989.

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