• 系统简介

CCS2000冷却系统设计用于冷藏并保持的代谢笼样品在或低于45华氏度(7摄氏度)。

 

• 产品由三部分组成
  

1）15个MMC100小鼠代谢笼；
2）笼架；
3）冷却装置。
它是为我们的标准代谢笼和笼架而设计的，因此，它提供了所有hatteras产品相同的质量和功能保证。

 

• 使用要求
  

尽管该系统是精心设计制作的，但是它的使用时很简单的。安装过程包括：将绝缘底座插入连接端口，将代谢笼放置到笼架上，给水槽中注水，和启动系统。就是这样。系统将自动开始制冷，以及维持与周围温度（室温）30度左右的温差。系统是可靠的和耐用的，不需要特殊的维护。

 

安装开始于制冷单元，制冷单元安装在笼架的底部，包含电子单元用来制冷和维持水的温度。还包括水槽，用来实现水循环。另外，该单元还包括一个控制器用来显示和控制温度水平。

 

笼架系统是一个支撑设施，包含铅管系统和制冷单元，作为代谢笼的连接点。笼架是铝质的，带有烤漆。3排水平结构，每个水平结构上带有5个小孔用来安装代谢笼。每一排的旁边的背板上是连接的端口，用来连接代谢笼的绝缘底座到铅管。制冷的绝缘底座为尿液样本提供制冷。笼子由丙烯酸零部件和不锈钢底板和独特设计的不锈钢收集漏斗组成。可以舒适的安全的连续24小时饲养一只小鼠，制冷的代谢笼提供和标准的代谢笼一样的收集能力。

 

• 产品特点

冷却尿液样本将确保几个用于研究的好处:
* 保持样品的质量；
* 消除细菌繁殖；
* 维持一个稳定的pH值；
* 保持样本的活性；
此外，制冷过程可保持温暖环境气候中的笼内环境冷却，从而为老鼠提供更舒适的空气

 

• 文献参考

Regulation of ENaC in mice lacking renal insulin receptors in the collecting duct
TS Pavlov, DV Ilatovskaya, V Levchenko, L Li… - The FASEB Journal, 2013 - FASEB

 

Reduced ENaC activity and blood pressure in mice with genetic knockout of the insulin receptor in the renal collecting duct
L Li, RM Garikepati, S Tsukerman… - American Journal of …, 2013 - Am Physiological Soc

 

Deletion of the Prorenin Receptor from the Ureteric Bud Causes Renal Hypodysplasia
R Song, G Preston, A Ichihara, IV Yosypiv - PloS one, 2013 - dx.plos.org

 

Renal protective effects of α-calcitonin gene-related peptide in deoxycorticosterone-salt hypertension
J Li, KA Carnevale, DJ DiPette… - American Journal of …, 2013 - Am Physiological Soc

 

Differential effects of dietary sodium intake on blood pressure and atherosclerosis in hypercholesterolemic mice
H Lu, C Wu, DA Howatt, A Balakrishnan… - The Journal of …, 2013 - Elsevier

 

Connective Tissue Growth Factor (CTGF) Expression Modulates Response to High Glucose
LR James, C Le, H Doherty, HS Kim, N Maeda - PloS one, 2013 - dx.plos.org

 

PGES-1-derived PGE2 mediates dehydration natriuresis
Z Jia, G Liu, Y Sun, Y Kakizoe, G Guan… - American Journal of …, 2013 - Am Physiological Soc

 

Effects of a New SGLT2 Inhibitor, Luseogliflozin, on Diabetic Nephropathy in T2DN Rats
N Kojima, JM Williams, T Takahashi, N Miyata… - … of Pharmacology and …, 2013 - ASPET

 

Bucktooth parrotfish< i> Sparisoma radians grazing on< i> Thalassia in Bermuda varies seasonally and with background nitrogen content
KK Holzer, DA Seekell, KJ McGlathery - Journal of Experimental Marine …, 2013 - Elsevier

 

Apelin retards the progression of diabetic nephropathy
RT Day, RC Cavaglieri… - American Journal of …, 2013 - Am Physiological Soc

 

Thyroid hormone is required for hypothalamic neurons regulating cardiovascular functions
J Mittag, DJ Lyons, J Sällström, M Vujovic… - The Journal of clinical …, 2013 - ncbi.nlm.nih.gov

 

Growth of Juvenile Scup Fed Two Commercial Diets
DM Perry, DH Redman, R Mercaldo-Allen… - … American Journal of …, 2013 - Taylor & Francis

 

The 70kD heat shock protein protects against experimental traumatic brain injury
JY Kim, N Kim, Z Zheng, JE Lee, MA Yenari - Neurobiology of disease, 2013 - Elsevier

 

Central insulin-Angiotensin II interaction in blood pressure regulation in fructose overloaded rats
MA Mayer, C Höcht, JF Giani, MC Muñoz, A Carranza… - Regulatory peptides, 2013 - Elsevier

 

Neurological and molecular biological characterisation of the mutant mouse line Tom40
RM Zeh - d-nb.info

 

Unintended Effects of Cardiovascular Drugs on the Pathogenesis of Alzheimer's Disease
J Wang, Z Zhao, E Lin, W Zhao, X Qian, D Freire… - PloS one, 2013 - dx.plos.org

 

ENU-induced Mutation in the DNA-binding Domain of KLF3 Reveals Important Roles for KLF3 in Cardiovascular Development and Function in Mice
L Kelsey, AM Flenniken, D Qu, APW Funnell… - PLoS genetics, 2013 - dx.plos.org

 

Lifelong Exposure to Bisphenol A Alters Cardiac Structure/Function, Protein Expression, and DNA Methylation in Adult Mice
BB Patel, M Raad, IA Sebag, LE Chalifour - Toxicological Sciences, 2013 - Soc Toxicology

 

MARINE BAITFISH
L Cortney, MAA DiMAggio - 2013 - flseagrant.org

 

Recruitment dynamics of Periphylla periphylla in the Trondheimsfjord
ÅL Borgersen - 2013 - diva-portal.org

 

FORMLESS ACCIDENT: A HAPPENING TOWARDS THE FALL
ANAM VALDERRAMA - 2013 - ideals.illinois.edu

 

 

 

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