新物体识别测试系统
型号:： XR-XX117
价格:请致电：010-57128832,18610462672
品牌: 上海    产品商标: 上海欣软

 

 介绍

新异物体识别测试系统是利用动物先天对新物体有探索倾向的原理而建立的学习记忆测试方法。该方法具有让老鼠在自由活动状态下进行学习记忆测试的特点，能更近似地模拟人类的学习记忆行为。同时，通过新物体（形状、大小等）的灵活变换该实验还允许测试动物长期或短期记忆机制的形成以及急物在特定阶段的记忆形成的影响评判。被广泛应用于学习记忆、老年痴呆、海马/外海马研究、智力与衰老、新药开发/筛选/评价、药理学、毒理学、预防医学、神经生物学、动物心理学及行为生物学等多个学科的科学研究和计算机辅助教学等领域，在世界上已经得到广泛地认可，是医学院校开展行为学研究尤其是学习与记忆研究的首选经典实验。

仪器特点

1．多种可靠的动物识别算法：传统灰度识别、轮廓识别、背景识别与多点识别，能够很好的应付各种复杂的实验背景，准确跟踪被测动物的运动轨迹。例如，我们可以通过多点识别（头部）来很好的检测动物对某兴趣物体的接近次数；

2．能够灵活设计出各种形状的实验区域，比如圆形、矩形、不规则多边形等，从而胜任更多动物行为实验的测试。例如，我们可以设计出六边形，开展六臂水***大学、四川大学      

指标参数

指标类型

指标名称

通用指标

活动路程、测试时间、速度、静止时间、静止时间比例

探索性指标

接触次数、接触潜伏期、接触持续时间、接近时间、最大距离、最短距离

其他指标

动态轨迹图、站立次数（手动记录）等

y explore for a set time.   A novel animal is placed in one of the two enclosures, and the percentage of time the mouse spends in the section with the novel animal is compared to the time spent in the section with the empty enclosure.   In a later session, the time spent with the same animal might be compared to time spent with a newer, more novel animal.
 
 
8. 条件性位置偏爱（Conditioned Place Preference）
   条件性位置偏爱实验（CPP）实验是目前评价药物精神依赖性的经典实验模型。该实验将实验动物（大鼠、小鼠）置于条件性位置偏爱箱的白色观察区，并给予精神依赖药物然后观察实验动物在条件性位置偏爱箱的黑色区和白色区的活动情况，白色区、黑色区以及其中的灰*之间有小门可供动物自由穿梭。动物每次处于给药区就会在药物奖赏性效应的作用下对黑色和白*域产生位置上的偏好，其程度与药物的精神依赖性相关。
    A drug is injected and the subject is introduced to distinctive environment A.  This procedure is repeated for several trials.   During these conditioning trials the animal develops an association between the subjective state produced by the drug (often drugs that produce mood elevation or euphoria in humans) and the contextual cues present while the drug is active.  To test the conditioning, the animal is placed in an apparatus with drug-related cues in one compartment and neutral cues in the other. nbsp; If conditioning occurred, the animal will move toward the compartment containing the drug-related cues.
In a Conditioned Place Preference experiment, subjects are returned to an apparatus were they can freely move between a compartment in which they were conditioned with drug-related cues, and a compartment with neutral cues.  If the conditioning was successful for positive, reinforcing drug states, they should spend more time in the compartment with drug-related cues。
In a Conditioned Place Aversion experiment, subjects are returned to an apparatus were they can freely move between a compartment in which they were conditioned with an aversive stimulus, such as a shock; and a compartment with neutral cues.  If the aversive conditioning was successful, they should spend more time in the compartment with neutral cues.