Nebramycin II; APRAMYCIN SULFATE;硫酸安普霉素;称阿泊拉霉素;Apramycin sulfate salt 英文名称: Apramycin sulfate salt 硫酸安普霉素 | |||||||||||||||||
型号:null 产品货号: Sigma A2024 | |||||||||||||||||
价格:请致电:010-57128832,18610462672 | |||||||||||||||||
品牌: sigma | |||||||||||||||||
APRAMYCIN SULFATE 硫酸安普霉素 Synonym: Nebramycin II; APRAMYCIN SULFATE;硫酸安普霉素;阿泊拉霉素;Apramycin sulfate salt Product Description Sigma Prod. No. A-2024 CAS NUMBER: 6 PHYSICAL PROPERTIES: Appearance: Faint yellow powder Molecular formula: C21H41N5O11 · x H2SO4 Molecular weight: 539.58 (free base) storage temp. : 2 assay: ~95.5% (TLC) Apramycin is an aminoglycoside antibiotic produced by a strain of Streptomyces tenebrarius. Thecompound is used as the sulfate in veterinary practice(通过干扰原核生物核蛋白质的合成而抑制细菌的繁殖) STABILITY / STORAGE AS SUPPLIED: Store desiccated at 2-8EC. SOLUBILITY / SOLUTION STABILITY: Aqueous solutions at 25 mg/mL are faint yellow. No solution stability data are currently available. APPLICATIONS: 1. An oral composition of 2. Under the Federal Food, Drug and Cosmetics Act, feed containing 3. Apramycin is a potent inhibitor of protein synthesis in bacteria in vivo and in vitro. To a limited extent, it induces translation errors in cell-free systems from Escherichia coli supplemented with poly(U). Apramycin also inhibits the translocation step of protein synthesis in vivo (e.g., in protoplasts of Bacillus megaterium), and in vitro (e.g., in cell-free systems from E. coli). This may be the drug’s primary inhibitory effect. 5 4. Apramycin sulfate is an aminocyclitol antibiotic whose antibacterial activity has been tested in comparison with neomycin and streptomycin. Of the strains tested, 99% were sensitive to apramycin sulfate, compared to 93% for neomycin and 48% for streptomycin. In vitro resistance development to apramycin sulfate was gradual Ordering Information
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