皮肤及组织生物力学柔软度测量分析仪系统
英文名称: Biomechanical Tissue Characterization system
型号:: BCT200
价格:请致电:010-57128832,18610462672
品牌: 美国    产品商标: surgical laboratory

 

BCT2000皮肤及组织生物力学特性(柔软度)测量分析仪系统绍

BCT2000组织柔软度测量仪是用来测量一定区域的皮肤或者凝胶组织在一个吸引强制力的作用下的变形以及恢复的能力,其测量样品的种类包括人类及动物皮肤、瘢痕及愈合组织、人工凝胶及植入假体,人工器官、橡胶薄膜、塑胶薄膜等多种材料。 
BCT2000组织柔软度测量仪的测量原理是通过在被测皮肤表面形成负压,使皮肤吸入测试探头,此探头有一对收发光管(激光收发装置),发光管的激光功率恒定,由于吸入皮肤的深度不同,接收管感应到的激光强度也不同,从而可以得到深度一气压差的曲线,通过分析此曲线就可以得到皮肤的弹性和粘弹性值。

BCT2000系统主要通过一个直径为10mm的探头对测量样品表面施加低压力吸入(0到150 mm Hg),然后被测量区域内的皮肤会被直径为2mm开放式的探头吸入。皮肤或者凝胶进入到探头的深度将会被激光测量系统无接触测量得到,这个测量是通过一个光学测量系统完成,它是由一个发光器和一个接收器组成的。整个测量过程的加压过程在5秒钟,释放压力过程为15秒钟,整个测量过程通过测量施加压力和释放压力过程中上移形变量最大值和残值之间的比率,可以分析皮肤或凝胶表面弹性的大小;通过分析其恢复时间和形变量,可以分析皮肤或凝胶柔软度。 
伴随皮肤美容学和临床治疗学的发展,皮肤弹性的无创性量化评价已经成为研究皮肤表面生物学状况的重要内容。应用BCT2000皮肤及组织柔软度测量仪系统对皮肤弹性进行无创性检测,结合对影响弹性因素超微结构的组织学及分子机制的研究,将使对各种状态下皮肤弹性的变化有更加全面、深入的了解。

 
图1 BCT2000皮肤及组织柔软度测量仪


图2 BCT2000的测量原理示意图


图3 BCT2000的测量过程施加压力和形变关系示意图


图4 BCT2000的测量过程施加压力和形变关系软件界面

·快门控制:电子快门

·接    口:标准C接口

·灵 敏 度:可检测出低于20pg经EB染色的双链DNA;

·配备进口6倍变焦镜头,便于凝胶的缩放观察;

F=1:1.2(2/3英寸)

·采用多层镀膜滤光镜组,有效滤除背景干扰噪声;

·紫外光源(石英紫外灯管)

·透射波长:300nm

·反射波长:254nm、365nm

·超薄(透射)鳞屏转换板和(反射)白光源;

·抽屉式活动胶台(配专用切胶罩),便于观察、操作、切胶;

·智能化控制暗箱:

·具有开门自动断紫外线功能、及用于切胶的紫外强制开关;

·自动延时关断

·具有对电动变焦镜头的驱动保护功能;RS232接口;

·可通过鼠标实现CCD设置和变焦镜头调整的遥控功能;

·系统由规范可靠的模块化部件组成,易于维修或更换部件;

·配品牌计算机和打印机。

 

kns/detail/detail.aspxQueryID=2&CurRec=127&recid=&FileName=1014325615.nh&DbName=CMFD201402&DbCode=CMFD&pr=" target="_blank">股前外侧皮瓣游离移植修复小腿及踝部皮肤软组织缺损的临床应用
16.硅胶乳房假体的选择与临床应用
17.化妆品保湿和皮肤弹性间的关系
18.移植合成表型平滑肌细胞改善皮肤弹性的组织工程学研究
19.PLGA静电纺丝纤维膜用于皮肤组织工程
20.miR-23b联合TGFβⅡ型受体拮抗剂治疗皮肤瘢痕的机制研究
21.UVB辐射敏感的致癌miR-365在皮肤鳞癌发生发展中作用机制的研究
22.利用金属蛋白质组学研究***结合蛋白及其在***皮肤毒性中的作用
23.肉毒杆菌素与皮肤柔软度和弹性的关系
主要优势 
1.对皮肤弹性测量为无创型测量,不会对皮肤或材料产生破坏
2.采用高分辨率激光(um)和负压(毫米和毫巴)传感器
4.测量方法简便快捷、技术实现成本较低
5.屏幕进行实时图形更新,可自动计算和自动显示测量结果
6.简单的触摸屏界面,测试流程简单
7.系统为便携式轻量化系统,容易携带,可提供实时数据和结果
8.可选择应力-应变计算,归一化面积和样品厚度
9.应用领域多样,包括对皮肤、软组织和伤口愈合、凝胶材料、薄膜材料等
10.用于输入和分析测试的软件兼容Windows系统,可直接连接打印机进行打印 
11.应用文献多,超过70篇重要文献 
主要参数 
1.样品数据获取速率:10 Hz
2.线性负压增加速率:10mmHg/second
3.系统最大负压压强:150 mmHg
4.气压传感器分辨率:0.01mmHg
5.真空泵气压范围:1 atm(标准大气压)
6.激光分辨率:3um
7.激光垂直位移范围:0-25 mm
8.电源输入100-240V
9.电源输出24V/2.91A
10.尺寸: 12英寸x10英寸x6英寸(30.48厘米*25.4厘米*15.24厘米)
11.重量:7.7kg 
参考文献

1)Measurement of change in the mechanical properties of burned skin to therapist intervention with a vacuum device. Gabriel V, Kowalske K. Burns. 2015 Jun;41(4):796-802.

2)Establishing a Reproducible Hypertrophic Scar following Thermal Injury: A Porcine Model. Scott J. Rapp, MD, Aaron Rumberg, BS, Marty Visscher, PhD, David A. Billmire, MD, Ann S. Schwentker, MD, and Brian S. Pan, MD. Plast Reconstr Surg Glob Open. 2015 Feb; 3(2): e309.

3)Silicone gel breast implants: science and testing. Kinney BM1, Jeffers LL, Ratliff GE, Carlisle DA. Plast Reconstr Surg. 2014 Jul;134(1 Suppl):47S-56S.

4)Viscoelastic Properties of Human Facial Skin- A Pilot Study. M.W. Beatty · A. Wee · D.B. Marx · L. Ridgway · B. Simetich. Conference Paper. IADR General Session and Exhibition 2014; 06/2014.

5)Viscoelastic properties measurement of the prolapsed anterior vaginal wall: a patient-directed methodology. Chuong CJ, Ma M, Eberhart RC, Zimmern P. Eur J Obstet Gynecol Reprod Biol. 2014 Feb;173:106-12.

6)Effect of Clostridial Collagenase Ointment on Healing, Scarring, and Granulation Tissue in Acute Wounds. David Mire, Herbert Slade, Kathy Weedon, Shai Rozen. Conference Paper: 2013 Clinical Symposium on Advances in Skin and Wound Care, At Orlando, Fl

7)A comparative study of the surgically relevant mechanical characteristics of the topical skin adhesives. Singer AJ, Perry L. Acad Emerg Med. 2012 Nov;19(11):1281-6.

8)LiquiBand ExceedTM Topical Skin Adhesive Summary of Effectiveness Data. J Alarcon, BSc (Hons), CCRA, G Miller, BSc (Hons). ADVANCED MEDICAL SOLUTIONS. web: us.liquiband.com.

9)Multimodal quantitative analysis of early pulsed-dye laser treatment of scars at a pediatric burn hospital. Bailey JK, Burkes SA, Visscher MO, Whitestone J, Kagan RJ, Yakuboff KP, Warner P, Randall Wickett R. Dermatol Surg. 2012 Sep;38(9):1490-6.

10)TOPICAL SKIN CARE FORMULATIONS. United States Patent. Hines et al. Patent No.: US 8,178,106. Date of Patent: May 15,2012.

11)In Vivo Btc-2000 Measurement of Anterior Vaginal Wall Biomechanical Properties in Prolapse Patients Undergoing Surgical Repair. Elizabeth Mosier, Rachel Jerome, Xian-Jin Xie, Charles CJ Chuong, J Yan, Robert C Eberhart and Philippe E Zimmern. J Biotechnol Biomaterial. Dec 07, 2011. 1:117

12)Antioxidants and Skin Aging: A Review. Christian Oresajo, PhD; Sreekumar Pillai, PhD; Margarita Yatskayer, MS; Germain Puccetti, PhD; David H. McDaniel, MD. Cosmetic Dermatology. November 2009 Vol. 22 No. 11.: 563-570.

13)In Vivo Study of Wound Bursting Strength and Compliance of Topical Skin Adhesives. Adam J. Singer MD, Larry C. Perry RN and Robert L. Allen Jr BS. Acad Emerg Med. 2008 Dec;15(12):1290-4.

14)Overexpression of mIGF-1 in Keratinocytes Improves Wound Healing and Accelerates Hair Follicle Formation and Cycling in Mice. Ekaterina Semenova, Heidi Koegel, Sybille Hasse, Jennifer E. Klatte, Esfir Slonimsky, Daniel Bilbao, Ralf Paus, Sabine Werner, and Nadia Rosenthal. Am J Pathol. 2008 Nov; 173(5): 1295–1310.

15)Lip care compositions. United States Patent. Wright et al. Pub. No.: US2008/0287540A1. Pub. Date: NOV. 20, 2008

16)Accelerated Wound Closure in Mice Deficient for Interleukin-10. Sabine A. Eming, Sabine Werner, Philippe Bugnon, Claudia Wickenhauser, Lisa Siewe, Olaf Utermhlen, Jeffrey M. Davidson, Thomas Krieg, and Axel Roers. Am J Pathol. 2007 Jan; 170(1): 188–202.

17)Development of a method for the evaluation of wound tensile strength in cynomolgus macaques. Joel B. Cornacoff, Kreg Howk, Bill Pikounis, Vince Mendenhall, Pauline Martin. Journal of Pharmacological and Toxicological Methods. 28 August 2007.

18)Accelerated Wound Closure in Mice Deficient for Interleukin-10. Sabine A. Eming,* Sabine Werner, Philippe Bugnon, Claudia Wickenhauser, Lisa Siewe,* Olaf Utermhlen,§ Jeffrey M. Davidson,|| Thomas Krieg,* and Axel Roers* Am J Pathol. 2007 January; 170(1): 188–202.

19)Evaluation of the multiple pass, low fluence algorithm for radiofrequency tightening of the lower face. Melissa A. Bogle, MD 1 2 *, Nathan Ubelhoer, DO 1 3, Robert A. Weiss, MD 4, Flor Mayoral, MD, Michael S. Kaminer, MD 1 Lasers in Surgery and Medicine. Volume 39, Issue 3 , Pages 210 – 217. 2007.

20)Surfactants in Personal Care Products and Decorative Cosmetics By Linda D. Rhein, Mitchell Schlossman, Ponisseril Somasundaran, Anthony O'Lenick. Published 2006 CRC Press. Chapter 3, Noninvasive Techniques to Measure Cutaneous Effects of Skin Care. Randall P. Wickett, PhD, Linda D. Rluein PhD, Svetlana Babajanyan MD.

21)Peroxiredoxin 6 Is a Potent Cytoprotective Enzyme in the Epidermis. Angelika Kümin, Christine Huber, Thomas Rülicke, Eckhard Wolf, and Sabine Werner. Am J Pathol. 2006 October; 169(4): 1194–1205.

22)Effect of Weight Loss on Cellulite: Gynoid Lypodystrophy. Smalls, Lola K. B.S.; Hicks, Matthew; Passeretti, David M.D.; Gersin, Keith M.D.; Kitzmiller, W John M.D.; Bakhsh, Adel M.D.; Wickett, R Randall Ph.D.; Whitestone, Jennifer M.S.; Visscher, Marty O. Ph.D. Plastic & Reconstructive Surgery. 118(2):510-516, August 2006.

23)COMPARISON BETWEEN LOW ENERGY, MULTIPLE PASS TECHNIQUE AND HIGH ENERGY, FEWER PASS TECHNIQUE WITH THERMACOOL SYSTEM FOR FACIAL REJUVENATION. Karen H. Kim, James Koch, and Roy G. Geronemus. Journal of American Society for Laser Medicine and Surgery Abstracts 2005 Page 3 #74.