Size  100ul
Cat code  220035
Species Cross-reactivity  H
Key Application  WB
Host  Mouse
Clone Number  5E12-C2-B7
Antibody type  Monoclonal antibody
Purified method  
Isotype  IgG1
Molecular Weight  59kDa
Sensitivity  The antibody detects endogenous level of G6PD protein.
Immunogen  Purified recombinant fragment of human G6PD expressed in E. Coli.
UniProt Number  P11413
GeneBank ID  NM_001042351.1
Subcellular location  
Formulation  Ascitic fluid containing 0.03% sodium azide.
Altername  G6PD; G6PD; G6PD_HUMAN; G6PD1; G6pdx; Glucose 6 phosphate 1 dehydrogenase; Glucose 6 phosphate dehydrogenase; Glucose 6 phosphate dehydrogenase, G6PD; Glucose-6-phosphate 1-dehydrogenase; MET19; POS10; Zwf1p;
Gene_symbol  G6PD1
Summary  This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniPort summary  Function  Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.acid and nucleic acid synthesis.
Application Images :  
Western blot detection of G6PD antibody in MCF7,Jurkat and Hela cell lysates using G6PD antibody (dilution 1:1000).Predicted band size:59 KDa.Observed band size:59KDa.