Size 100ul
Cat code 300787
Species Cross-reactivity H,M,R,Mk
Key Application WB
Host Rabbit
Clone Number
Antibody type polyclonal antibody
Purified method Affinity purified
Isotype
Molecular Weight 30kDa
Sensitivity This antibody detects endogenous levels of ANXA5 and does not cross-react with related proteins.
Immunogen Purified recombinant human ANXA5 protein fragments expressed in E.coli.
UniProt Number P08758
GeneBank ID NM_001154
Subcellular location
Formulation Purified Rabbit polyclonal in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Altername Anchorin CII;Annexin 5;Annexin A5;Annexin V;Annexin-5;Annexin5;AnnexinA5;AnnexinV;ANX 5;ANX A5;ANX5;ANXA5;ANXA5_HUMAN;Calphobindin I;CBP I;CBP-I;Endonexin II;ENX 2;ENX2;Lipocortin V;PAP I;PAP-I;Placental anticoagulant protein 4;Placental anticoagulant protein I ;PLACENTAL PROTEIN 4;PP 4;PP4;Thromboplastin inhibitor;VAC alpha;VAC-alpha ;Vascular anticoagulant alpha;Vascular anticoagulant-alpha.
Gene_symbol PP4;ANX5;ENX2;RPRGL3.
Summary The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways.Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction,inflammation,growth and differentiation.Annexin 5 has also been described as placental anticoagulant protein I,vascular anticoagulant-alpha,endonexin II,lipocortin V,placental protein 4 and anchorin CII.The gene spans 29 kb containing 13 exons,and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.[provided by RefSeq,Jul 2008]
UniPort summary Function This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex,which is involved in the blood coagulation cascade.
Application Images :

Western blot detection of ANXA5 antibody in 3T3,Hela,C6,COS7 and MCF7 cell lysates using ANXA5 antibody (1:2000 diluted).Predicted band size:30KDa.Observed band size:30KDa.Exposure time:20s.